Neurological disorders due to toxicity

Subcategories

• 8D43.0 Encephalopathy due to toxicity
• 8D43.1 Cognitive impairment due to toxicity

  These are conditions of impaired cognition due to the toxicity of substances. [1]

• 8D43.2 Neuropathy due to toxicity

  In considering the diagnosis of toxic neuropathy, two criteria should be met: (1) Exposure can be verified and temporally related to the onset of clinical symptoms. Neuropathic symptoms usually occur concurrently with the exposure or following a variable latency of up to several months. (2) There must be neurological signs and abnormal electrodiagnostic studies, because many toxic neuropathies are subclinical, subjective symptoms may or may not occur. Removal from exposure results in cessation of progression of symptoms and the deficit. Most toxins produce symmetrical axonal degeneration in a length-dependent pattern, beginning in the distal segments of the long and large-calibre nerve fibres eventually spreading proximally with continued exposure. In addition to motor and/or sensory deficits, severe pain may be a characteristic feature. [1]

• 8D43.3 Myopathy due to toxicity
• 8D43.4 Movement disorders due to toxicity

  Movements of the body such as hyperkinesias, dyskinesias, myoclonus, chorea, tremor and tics produced by toxicity either by toxin or drug, e.g. toxicity by manganese, neuroleptic drugs, calcium channel blockers, gastrointestinal prokinetics, antiarrhythmics and antidepressants that may induce Parkinsonism. [1]

• 8D43.5 Cassava poisoning

  Symmetrical, non-progressive, non-remitting spastic paraparesia occurring in epidemic and endemic forms with a predilection for children and young women. The unknown aetiology is related to consumption of bitter cassava roots with very minimal protein supplementation. [1]

References

1. World Health Organization. International Classification of Diseases, 11th Revision, for Mortality and Morbidity Statistics (ICD-11 MMS), 2026-01 release. World Health Organization; 2026.

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